Picasso has performed at major music festivals such as Ultra Music Festival and Tomorrowland. He has been performing in big clubs since he was 16 years old, has opened for acts like Swedish House Mafia and began headlining his own shows. On 27 April 2015, he released "Can't Stop" as a single with fellow producer Tom Tyger via Mixmash Records. On 16 November 2015, Picasso released "Want It Back (Origami)" as a single.
On 29 June 2016, he released a single titled "Final Call" through Armada Music under exclusive license from Protocol Recordings, a label run by Nicky Romero. The song peaked on Billboard's Dance/Mix Show Airplay chart at 39. An official music video was published by Protocol Recordings, it was directed by Fauns / Clubbing Vision. On 23 November 2016, it was announced that Picasso signed a deal with Spinnin' Records, with whom he released a single titled "Cracked Wall" on 2 December 2016.